Cannabinoids hold promise for treating health problems related to inflammation and chronic pain in dogs, in particular cannabidiol (CBD), and
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Pharmacokinetics of cannabidiol, cannabidiolic acid, delta-9-tetrahydrocannabinolic acid and related metabolites in canine serum after dosing with three oral forms of hemp extract
Cannabidiol (CBD)-rich hemp extract use is increasing in veterinary medicine with little examination of serum cannabinoids. Many products contain small
The interplay between first-pass effect and lymphatic absorption of cannabidiol and its implications for cannabidiol oral formulations
For highly lipophilic drugs, passage into the intestinal lymphatic system rather than the portal vein following oral administration may represent
Simple and Fast Gas-chromatography Mass Spectrometry Assay to Assess Delta 9-Tetrahydrocannabinol and Cannabidiol in Dogs Treated with Medical Cannabis for Canine Epilepsy
Background: To date, an increasing number of pet owners, especially in the USA, are using cannabis-derived products containing generally delta
Pharmacokinetic and safety evaluation of various oral doses of a novel 1:20 THC:CBD Cannabis herbal extract in dogs
Objective: To determine the pharmacokinetics (PK) and safety of various oral doses of a Cannabis herbal extract (CHE) containing a
Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats
The use of CBD-rich hemp products is becoming popular among pet owners with no long-term safety data related to consumption
Safety and tolerability of escalating cannabinoid doses in healthy cats
Objectives: The aim of this study was to determine the safety and tolerability of escalating doses of orally delivered cannabis
Current review of hemp-based medicines in dogs
Medical use of Cannabis (or hemp) began thousands of years ago. In the 20th century, mechanisms of action were demonstrated
Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process
There was consensus that medical cannabis may be considered for patients experiencing neuropathic, inflammatory, nociplastic, and mixed pain. Three treatment
Role of cannabinoid receptor type 1 in tibial and pudendal neuromodulation of bladder overactivity in cats
The role of cannabinoid type 1 (CB1) receptors in tibial and pudendal neuromodulation of bladder overactivity induced by intravesical infusion
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