Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are
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CATEGORY : Osteoarthritis
Delta-9-tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPARy and CB1 receptors
Background and Purpose Δ9-Tetrahydrocannabinolic acid (Δ9-THCA-A), the precursor of Δ9-THC, is a non-psychotropic phytocannabinoid that shows PPARγ agonist activity. Here,
Oral Transmucosal Cannabidiol Oil Formulation as Part of a Multimodal Analgesic Regimen: Effects on Pain Relief and Quality of Life Improvement in Dogs Affected by Spontaneous Osteoarthritis
The aim of this study was to evaluate the efficacy of oral transmucosal (OTM) cannabidiol (CBD), in addition to a
Evaluation of the Effect of Cannabidiol on Naturally Occurring Osteoarthritis-Associated Pain: A Pilot Study in Dogs
The objective of this study was to provide preliminary data describing the safety and effect of cannabidiol (CBD) for symptom
The Use of Cannabidiol-Rich Hemp Oil Extract to Treat Canine Osteoarthritis-Related Pain: A Pilot Study
Abstract The objective of this 90-day pilot clinical trial was to assess the impact of a full-spectrum product containing hemp
A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain
Abstract Over the last 2 decades, affirmative diagnoses of osteoarthritis (OA) in the United States have tripled due to increasing
Characterization of endocannabinoids and related acylethanolamides in the synovial fluid of dogs with osteoarthritis: a pilot study
Abstract Background Cannabis-based drugs have been shown to be effective in inflammatory diseases. A number of endocannabinoids including N- arachidonoylethanolamide
Pharmacokinetics, Safety and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
Abstract Objectives: The objectives of this study were to determine basic oral pharmacokinetics, and assess safety and analgesic efficacy of a
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