Abstract Cannabis has the potential to modulate some of the most common and debilitating symptoms of cancer and its treatments,
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Targeting the Endocannabinoid System for Prevention or Treatment of Chemotherapy-Induced Neuropathic Pain: Studies in Animal Models
Abstract There is a scarcity of drugs to either prevent or properly manage chemotherapy-induced neuropathic pain (CINP). Cannabis or cannabinoids
Cannabinoids As Potential Treatment for Chemotherapy-Induced Nausea and Vomiting
Abstract Despite the advent of classic anti-emetics, chemotherapy-induced nausea is still problematic, with vomiting being somewhat better managed in the
The heterogeneity and complexity of Cannabis extracts as antitumor agents
Abstract The Cannabis plant contains over 100 phytocannabinoids and hundreds of other components. The biological effects and interplay of these Cannabis compounds are not
Anti-tumour actions of cannabinoids
Abstract The endocannabinoid system has emerged as an important target for the treatment of many diverse diseases. In addition to
The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications
Abstract Prostate cancer is a global public health problem, and it is the most common cancer in American men and
Spilanthes acmella inhibits inflammatory responses via inhibition of NF-κB and MAPK signaling pathways in RAW 264.7 macrophages
Abstract Spilanthes acmella Murr. (S. acmella) has been used traditionally in India and Sri Lanka to treat various inflammatory diseases.
NSAIDs, Opioids, Cannabinoids and the Control of Pain by the Central Nervous System
Abstract Nonsteroidal anti-inflammatory drugs (NSAIDs) act upon peripheral tissues and upon the central nervous system to produce analgesia. A major
Medical Cannabis for Neuropathic Pain
Abstract Purpose of review: Many cultures throughout history have used cannabis to treat a variety of painful ailments. Neuropathic pain is
Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa
Abstract Cyclooxygenase enzymes (COX-1 and COX-2) catalyse the production of prostaglandins from arachidonic acid. Prostaglandins are important mediators in the
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