Abstract Epilepsy is considered to be one of the most common non-communicable neurological diseases especially in low to middle-income countries.
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Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity
Abstract Objective: To characterize the functional brain changes involved in δ-9-tetrahydrocannabinol (THC) modulation of chronic neuropathic pain. Methods: Fifteen patients with chronic
Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy
Abstract Objective: To assess the effect of oral cannabidiol (CBD) administration in addition to conventional antiepileptic treatment on seizure frequency in
Functional neuroanatomy of the endocannabinoid system
Abstract Several components of the endocannabinoid system have been fully characterized. Among them are two types of cannabinoid receptors (termed
Endocannabinoid System and Migraine Pain: An Update
The trigeminovascular system (TS) activation and the vasoactive release from trigeminal endings, in proximity of the meningeal vessels, are considered
The Endocannabinoid System and Autism Spectrum Disorders: Insights from Animal Models
Abstract Autism spectrum disorder (ASD) defines a group of neurodevelopmental disorders whose symptoms include impaired communication and social interaction with
Immunolocalization of cannabinoid receptor 1 (CB1), monoglyceride lipase (MGL) and fatty-acid amide hydrolase 1 (FAAH) in the pig claustrum
Abstract The claustrum (Cl) is a subcortical nucleus present in all mammalian species examined so far, whose function is still
Long-Term Aberrations To Cerebellar Endocannabinoids Induced By Early-Life Stress
Abstract Emerging evidence points to the role of the endocannabinoid system in long-term stress-induced neural remodeling with studies on stress-induced
The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis
Abstract Endocannabinoids (ECs) are involved in immunomodulation, neuroprotection and control of inflammation in the central nervous system (CNS). Activation of
Cellular Distribution of Canonical and Putative Cannabinoid Receptors in Canine Cervical Dorsal Root Ganglia
Growing evidence indicates cannabinoid receptors as potential therapeutic targets for chronic pain. Consequently, there is an increasing interest in developing
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