Abstract Marijuana has been used in medicine for millennia, but it was not until 1964 that delta9-tetrahydrocannabinol (delta9-THC), its major
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CATEGORY : Oncology
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil.
Abstract Cannabinoids (CBs) have been found to exert antiproliferative effects upon a variety of cancer cells, including colorectal carcinoma cells.
Cannabidiol, a Non-Psychoactive Cannabinoid Compound, Inhibits Proliferation and Invasion in U87-MG and T98G Glioma Cells through a Multitarget Effect
Abstract In the present study, we found that CBD inhibited U87-MG and T98G cell proliferation and invasiveness in vitro and
Cannabidiol inhibits angiogenesis by multiple mechanisms
Abstract Background and purpose: Several studies have demonstrated anti-proliferative and pro-apoptotic actions of cannabinoids on various tumours, together with their anti-angiogenic
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Abstract Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is
Anti-tumoural actions of cannabinoids
Abstract The endocannabinoid system has emerged as an important target for the treatment of many diverse diseases. In addition to
Cannabinoids as anticancer therapeutic agents
Abstract The recent announcement of marijuana legalization in Canada spiked many discussions about potential health benefits of Cannabis sativa. Cannabinoids are
Cannabinoids and cancer: pros and cons of an antitumour strategy
Abstract In the last two decades, research has dramatically increased the knowledge of cannabinoids biology and pharmacology. In mammals, compounds
The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells
Abstract Cannabis is the most widely used illicit drug in the world. Cannabinoids are used therapeutically by some patients as
Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana.
Abstract The ATP-dependent drug efflux transporter P-glycoprotein (P-gp) plays a significant role in the absorption and disposition of many compounds.
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