Cannabis is more than simply Δ9-tetrahydrocannabinol
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The Endocannabinoid System as an Emerging Target of Pharmacotherapy
Apr 21, 2021
Abstract The recent identification of cannabinoid receptors and their endogenous lipid ligands has triggered an exponential growth of studies exploring...
Cannabis, a complex plant: different compounds and different effects on individuals
Apr 21, 2021
Abstract Cannabis is a complex plant, with major compounds such as delta-9-tetrahydrocannabinol and cannabidiol, which have opposing effects. The discovery...
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
Apr 21, 2021
Abstract Cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. This review...
Ubiquitous expression of cyclooxygenase-2 in meningiomas and decrease in cell growth following in vitro treatment with the inhibitor celecoxib: potential therapeutic application
Apr 21, 2021
Abstract Object: Meningiomas are the second most common symptomatic primary central nervous system tumor in adults. Findings of epidemiological studies link...
The Effects of Dosage-Controlled Cannabis Capsules on Cancer-Related Cachexia and Anorexia Syndrome in Advanced Cancer Patients: Pilot Study
Apr 21, 2021
Abstract Background: Cancer-related cachexia and anorexia syndrome (CACS) is a common phenomenon in cancer patients. Cannabis has been suggested to...
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines
Apr 21, 2021
Abstract Orally applicable Delta9-tetrahydrocannabinol and its synthetic derivatives have been used as antiemetic drugs during chemotherapy in cancer patients. However,...
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism
Apr 21, 2021
Abstract Gemcitabine (GEM, 2′,2′-difluorodeoxycytidine) is currently used in advanced pancreatic adenocarcinoma, with a response rate of < 20%. The purpose...
Ganoderma: A Cancer Immunotherapy Review
Apr 21, 2021
Abstract Ganoderma is a significant source of natural fungal medicines and has been used for the treatment of various diseases for...
Antitumor Cannabinoid Chemotypes: Structural Insights
Apr 21, 2021
Abstract Cannabis has long been known to limit or prevent nausea and vomiting, lack of appetite, and pain. For this...
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