Opportunities for cannabis in supportive care in cancer
Abstract Cannabis has the potential to modulate some of the most common and debilitating symptoms of cancer and its treatments,...
Targeting the Endocannabinoid System for Prevention or Treatment of Chemotherapy-Induced Neuropathic Pain: Studies in Animal Models
Apr 21, 2021
Abstract There is a scarcity of drugs to either prevent or properly manage chemotherapy-induced neuropathic pain (CINP). Cannabis or cannabinoids...
Cannabinoids As Potential Treatment for Chemotherapy-Induced Nausea and Vomiting
Apr 21, 2021
Abstract Despite the advent of classic anti-emetics, chemotherapy-induced nausea is still problematic, with vomiting being somewhat better managed in the...
The heterogeneity and complexity of Cannabis extracts as antitumor agents
Apr 21, 2021
Abstract The Cannabis plant contains over 100 phytocannabinoids and hundreds of other components. The biological effects and interplay of these Cannabis compounds are not...
Anti-tumour actions of cannabinoids
Apr 21, 2021
Abstract The endocannabinoid system has emerged as an important target for the treatment of many diverse diseases. In addition to...
Spilanthes acmella inhibits inflammatory responses via inhibition of NF-κB and MAPK signaling pathways in RAW 264.7 macrophages
Apr 21, 2021
Abstract Spilanthes acmella Murr. (S. acmella) has been used traditionally in India and Sri Lanka to treat various inflammatory diseases....
NSAIDs, Opioids, Cannabinoids and the Control of Pain by the Central Nervous System
Apr 21, 2021
Abstract Nonsteroidal anti-inflammatory drugs (NSAIDs) act upon peripheral tissues and upon the central nervous system to produce analgesia. A major...
Medical Cannabis for Neuropathic Pain
Apr 21, 2021
Abstract Purpose of review: Many cultures throughout history have used cannabis to treat a variety of painful ailments. Neuropathic pain is...
Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa
Apr 21, 2021
Abstract Cyclooxygenase enzymes (COX-1 and COX-2) catalyse the production of prostaglandins from arachidonic acid. Prostaglandins are important mediators in the...
Cannabinoids as novel anti-inflammatory drugs
Apr 21, 2021
Abstract Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as...
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