Trial of Cannabidiol for Drug-Resistant Seizuresin the Dravet Syndrome
Abstract Background: The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high...
Endocannabinoids in the Gut
Oct 18, 2023
Cannabis has been used medicinally for centuries to treat a variety of disorders, including those associated with the gastrointestinal tract....
Facilitating the Bloom of Intestinal Flora: Observing the Influence of Tetrahydrocannabinol (THC) on Beneficial Bacteria Inhabiting the Intestinal Microbiota
Oct 18, 2023
Healthy human bodies are inhabited by over 100 trillion bacterial cells. The study of the symbiotic relationship between humans and...
Why Do Marijuana and Synthetic Cannabimimetics Induce Acute Myocardial Infarction in Healthy Young People?
Oct 18, 2023
The use of cannabis preparations has steadily increased. Although cannabis was traditionally assumed to only have mild vegetative side effects,...
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain
Sep 21, 2022
Abstract Anandamide, an endocannabinoid, is degraded by the enzyme fatty acid amide hydrolase which can be inhibited by nonsteroidal anti-inflammatory...
Ingestion of a THC-rich cannabis oil in people with fibromyalgia: A randomized, double-blind, placebo-controlled clinical trial
Aug 17, 2022
Objective To determine the benefit of a tetrahydrocannabinol (THC)-rich cannabis oil on symptoms and quality of life of fibromyalgia patients....
A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain
Aug 17, 2022
We report a systematic review and meta-analysis of studies that assessed the antinociceptive efficacy of cannabinoids, cannabis-based medicines, and endocannabinoid...
Motivations and expectations for using cannabis products to treat pain in humans and dogs: a mixed methods study
Aug 17, 2022
Background: Social media and academic literature suggest that more people are using cannabis to treat their own or their dog’s...
Opioids/cannabinoids as a potentialtherapeutic approach in COVID-19 patients.
Aug 10, 2022
Opioids and cannabinoids are a group of endogenous and exogenous compounds that function through activation of their respective receptors (opioid...
Cannabidiol, a major non-psychotropic cannabis constituent enhances fracture healing and stimulates hydroxylase activity in osteoblasts
Aug 10, 2022
Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are...
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