Cardiovascular System Effects of Marijuana
Marijuana and Δ9-tetrahydrocannabinol (THC) increase heart rate, slightly increase supine blood pressure, and on occasion produce marked orthostatic hypotension. Cardiovascular...
Acute effects of oral delta-9-tetrahydrocannabinol (THC) on autonomic cardiac activity and their relation to subjective and anxiogenic effects
Aug 9, 2022
Cannabis is the most commonly used psychotropic drug in the United States, after alcohol. Despite its apparent sedative and calming...
Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors
Aug 9, 2022
Posttraumatic stress disorder (PTSD) is an incapacitating syndrome that follows a traumatic experience. Predator exposure promotes long-lasting anxiogenic effect in...
Effects of alprazolam and cannabinoid-related compounds in an animal model of panic attack
Aug 9, 2022
Selective stimulation of carotid chemoreceptors by intravenous infusion of low doses of potassium cyanide (KCN) produces short-lasting escape responses that...
Effects of Cannabis Use on Sedation Requirements for Endoscopic Procedures
Apr 21, 2021
Abstract Context: Cannabis (or marijuana) became legal for recreational use in Colorado in 2012, and this legislation change has created both...
Circulating Endocannabinoids: From Whence Do They Come and Where are They Going?
Apr 21, 2021
Abstract The goal of this review is to summarize studies in which concentrations of circulating endocannabinoids in humans have been...
The Combination of Cannabidiol and Δ – Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model
Apr 21, 2021
Abstract High-grade glioma is one of the most aggressive cancers in adult humans and long-term survival rates are very low...
Cannabinoids Promote Progression of HPV-Positive Head and Neck Squamous Cell Carcinoma via p38 MAPK Activation
Apr 21, 2021
Abstract Purpose: Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is associated with daily marijuana use and is also...
Report of Objective Clinical Responses of Cancer Patients to Pharmaceutical-grade Synthetic Cannabidiol
Apr 21, 2021
Abstract Background/aim: Cannabinoids are widely used in the management of pain, nausea and cachexia in cancer patients. However, there has been...
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine
Apr 21, 2021
Abstract The life expectancy for pancreatic cancer patients has seen no substantial changes in the last 40 years as very...
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