Abstract Gemcitabine (GEM, 2′,2′-difluorodeoxycytidine) is currently used in advanced pancreatic adenocarcinoma, with a response rate of < 20%. The purpose...
Abstract Cannabigerol (CBG) is a safe non-psychotropic Cannabis-derived cannabinoid (CB), which interacts with specific targets involved in carcinogenesis. Specifically, CBG...
Abstract Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%....
Abstract Background and purpose: Several studies have demonstrated anti-proliferative and pro-apoptotic actions of cannabinoids on various tumours, together with their anti-angiogenic...
Abstract Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is...
Abstract The endocannabinoid system has emerged as an important target for the treatment of many diverse diseases. In addition to...
Abstract The recent announcement of marijuana legalization in Canada spiked many discussions about potential health benefits of Cannabis sativa. Cannabinoids are...
Abstract In the last two decades, research has dramatically increased the knowledge of cannabinoids biology and pharmacology. In mammals, compounds...
Abstract Cannabis is the most widely used illicit drug in the world. Cannabinoids are used therapeutically by some patients as...
Abstract Background: Cannabis is the most widely used illicit drug in the world that is often used by cancer patients in...