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Activation of cannabinoid 2 receptor relieves colonic hypermotility in a rat model of irritable bowel syndrome

Home Activation of cannabinoid 2 receptor relieves colonic hypermotility in a rat model of irritable bowel syndrome

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Activation of cannabinoid 2 receptor relieves colonic hypermotility in a rat model of irritable bowel syndrome

  • By: Lin M, Chen L, Xiao Y, Yu B.
  • Published On: 21 February, 2019
  • Publication: pubmed
  • Tags: general
  • Category: Gastroenterology

CB2 receptor may exert an important inhibitory effect in stress-induced colonic hypermotility by modulating NO synthesis through p38 mitogen-activated protein kinase signaling. AM1241 could be used as a potential drug to treat disorders with colonic hypermotility.

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