Cannabinoids for cancer treatment: progress and promise
Abstract Cannabinoids are a class of pharmacologic compounds that offer potential applications as antitumor drugs, based on the ability of...
Cannabinoids and Cancer
Apr 21, 2021
Abstract Marijuana has been used in medicine for millennia, but it was not until 1964 that delta9-tetrahydrocannabinol (delta9-THC), its major...
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil.
Apr 21, 2021
Abstract Cannabinoids (CBs) have been found to exert antiproliferative effects upon a variety of cancer cells, including colorectal carcinoma cells....
Cannabidiol, a Non-Psychoactive Cannabinoid Compound, Inhibits Proliferation and Invasion in U87-MG and T98G Glioma Cells through a Multitarget Effect
Apr 21, 2021
Abstract In the present study, we found that CBD inhibited U87-MG and T98G cell proliferation and invasiveness in vitro and...
Cannabidiol inhibits angiogenesis by multiple mechanisms
Apr 21, 2021
Abstract Background and purpose: Several studies have demonstrated anti-proliferative and pro-apoptotic actions of cannabinoids on various tumours, together with their anti-angiogenic...
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Apr 21, 2021
Abstract Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is...
Anti-tumoural actions of cannabinoids
Apr 21, 2021
Abstract The endocannabinoid system has emerged as an important target for the treatment of many diverse diseases. In addition to...
Cannabinoids as anticancer therapeutic agents
Apr 21, 2021
Abstract The recent announcement of marijuana legalization in Canada spiked many discussions about potential health benefits of Cannabis sativa. Cannabinoids are...
Cannabinoids and cancer: pros and cons of an antitumour strategy
Apr 21, 2021
Abstract In the last two decades, research has dramatically increased the knowledge of cannabinoids biology and pharmacology. In mammals, compounds...
The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells
Apr 21, 2021
Abstract Cannabis is the most widely used illicit drug in the world. Cannabinoids are used therapeutically by some patients as...
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